SYDE2

Across TCGA cell cohorts, SYDE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,677 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SYDE2-associated GO terms across cancer lineages are RNA destabilization, Protein localization to vacuole, and Regulation of nucleobase-containing compound transport. Each is linked with SYDE2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SYDE2-to-partner and partner-to-SYDE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA destabilization grouped by SYDE2-low versus SYDE2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYDE2→partner) and Y-score (partner→SYDE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RNA destabilization →	+0.055	+0.626	<.001	.003	3	10
OVARY	Protein localization to vacuole →	+0.055	+0.713	.003	.002	3	9
OVARY	Regulation of nucleobase-containing compound transport →	+0.088	+0.638	.001	.002	3	9
SKIN	Regulation of Schwann cell differentiation →	+0.093	+0.430	.003	.002	3	9
LARGE_INTESTINE	Random inactivation of X chromosome →	+0.074	+0.623	.004	.006	3	9
SOFT_TISSUE	Taxis →	-0.055	-0.658	.005	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,677 associations by consensus.

RNA destabilization by SYDE2 expression — LARGE_INTESTINE

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