SYDE1

Across TCGA cell cohorts, SYDE1 mutation is significantly associated with the drug of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SYDE1-associated genes across cancer lineages are 123829, ETP-45835, and GSK2110183B. Each is linked with SYDE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYDE1-to-partner and partner-to-SYDE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 123829 grouped by SYDE1-low versus SYDE1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYDE1→partner) and Y-score (partner→SYDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	123829 →	+0.709	+2.871	.009	.021	3	1
LARGE_INTESTINE	ETP-45835 →	+0.275	+2.684	.015	.035	3	1
LARGE_INTESTINE	GSK2110183B →	+0.609	+2.871	.035	.021	2	1
LARGE_INTESTINE	Teniposide →	+0.604	+2.871	.016	.021	2	1
LARGE_INTESTINE	Docetaxel →	+1.110	+2.807	.018	.045	2	1
LARGE_INTESTINE	Voxtalisib →	+0.329	+2.874	.012	.021	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

123829 by SYDE1 expression — LARGE_INTESTINE

Explore this box plot interactively →