Across TCGA cell cohorts, SYCP2 mutation is significantly associated with the RNA expression of many other genes, with 93 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SYCP2-associated genes across cancer lineages are SPACA1, CXorf66, and GAGE12E. Each is linked with SYCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYCP2-to-partner and partner-to-SYCP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYCP2→partner) and Y-score (partner→SYCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SPACA1 →	+0.017	+4.285	<.001	.007	3	2
UPPER_AERODIGESTIVE_TRACT	CXorf66 →	+0.045	+4.357	<.001	.006	3	2
LUNG_NSCLC_LUSC	GAGE12E →	+0.076	+4.643	<.001	.008	3	1
PANCREAS	SORCS3 →	+0.188	+3.959	<.001	.004	3	1
PANCREAS	CA4 →	+0.717	+3.665	.001	.004	3	1
PANCREAS	ADH1A →	+0.481	+3.222	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 93 associations by consensus.

Exploration

SYCP2 survival (RNA) · tumor vs normal (RNA) · all SYCP2 data types