Across TCGA patient cohorts, SYCE3 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYCE3-associated genes across cancer lineages are IGKV1OR-2, SSTR5, and RNU6-1252P. Each is linked with SYCE3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYCE3-to-partner and partner-to-SYCE3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYCE3→partner) and Y-score (partner→SYCE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1OR-2 →	+0.260	+3.393	.009	.007	3	1
UCEC	SSTR5 →	+1.212	+3.608	<.001	.009	3	1
COAD	RNU6-1252P →	+0.526	+7.741	<.001	.009	3	1
COAD	TSPY15P →	+0.084	+7.741	<.001	.009	3	1
COAD	RNA5SP489 →	+0.518	+7.741	<.001	.009	3	1
COAD	OR5J7P →	+0.314	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

SYCE3 survival (RNA) · tumor vs normal (RNA) · all SYCE3 data types