SYCE1

Across TCGA patient cohorts, SYCE1 protein abundance is significantly associated with the RNA expression of many other genes, with 393 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SYCE1-associated genes across cancer lineages are CSNK2A1, CCM2L, and VAPA. Each is linked with SYCE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYCE1-to-partner and partner-to-SYCE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYCE1 versus CSNK2A1 in PDAC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYCE1→partner) and Y-score (partner→SYCE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CSNK2A1 →	+0.328	+1.014	.004	.006	3	1
PDAC	CCM2L →	-0.542	-1.309	<.001	<.001	3	1
PDAC	VAPA →	+0.598	+1.200	.001	<.001	3	1
PDAC	RNMT →	+0.625	+1.135	<.001	<.001	3	1
PDAC	LIPG →	-0.669	-1.156	.005	.002	3	1
PDAC	INTS6 →	+0.298	+0.856	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 393 associations by consensus.

SYCE1 vs CSNK2A1 — PDAC

Explore this scatter interactively →