SYCE1

Across TCGA cell cohorts, SYCE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,092 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SYCE1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Positive regulation of intracellular estrogen receptor signaling pathway, and RNA catabolic process. Each is linked with SYCE1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SYCE1-to-partner and partner-to-SYCE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by SYCE1-low versus SYCE1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYCE1→partner) and Y-score (partner→SYCE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Pre-mRNA catabolic process →	+0.127	+0.110	.001	.008	2	8
LARGE_INTESTINE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.123	+0.144	<.001	.001	3	6
OESOPHAGUS	RNA catabolic process →	+0.058	+0.178	<.001	.004	3	5
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.077	+0.119	.001	<.001	2	6
SOFT_TISSUE	Regulation of mRNA catabolic process →	+0.047	+0.897	<.001	.003	3	5
LARGE_INTESTINE	mRNA alternative polyadenylation →	+0.063	+0.128	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,092 associations by consensus.

Pre-mRNA catabolic process by SYCE1 expression — URINARY_TRACT

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