SYBU

Across TCGA cell cohorts, SYBU RNA expression is significantly associated with the go_rna of many other GO terms, with 3,470 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SYBU-associated GO terms across cancer lineages are UDP-galactose transmembrane transport, Mitochondrial electron transport, cytochrome c to oxygen, and Response to laminar fluid shear stress. Each is linked with SYBU in more than 7 cancer types. Because this analysis shows association rather than direction, both SYBU-to-partner and partner-to-SYBU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UDP-galactose transmembrane transport grouped by SYBU-low versus SYBU-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYBU→partner) and Y-score (partner→SYBU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UDP-galactose transmembrane transport →	+0.091	+1.063	<.001	<.001	3	8
CNS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.063	+1.566	<.001	.001	3	7
SKIN	Response to laminar fluid shear stress →	+0.073	+1.468	<.001	<.001	3	7
BLOOD_Leukemia	Activation of protein kinase A activity →	+0.114	+0.641	<.001	.001	3	7
KIDNEY	Positive regulation of cellular respiration →	+0.152	+1.433	<.001	.003	3	7
LARGE_INTESTINE	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.187	+1.446	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,470 associations by consensus.

UDP-galactose transmembrane transport by SYBU expression — LARGE_INTESTINE

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