SWT1

Across TCGA patient cohorts, SWT1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,956 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SWT1-associated genes across cancer lineages are SLC39A6, CTSZ, and ST8SIA5. Each is linked with SWT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SWT1-to-partner and partner-to-SWT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SWT1 versus SLC39A6 in BRCA, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SWT1→partner) and Y-score (partner→SWT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC39A6 →	-2.911	-0.313	.002	.001	3	1
LSCC	CTSZ →	-0.822	-0.716	<.001	.004	3	1
LSCC	ST8SIA5 →	+0.261	+0.876	.009	<.001	3	1
LSCC	TAF7L →	+1.382	+0.842	.003	.005	3	1
LSCC	FGF14 →	-0.845	-0.655	<.001	<.001	3	1
LSCC	FGF9 →	-0.481	-0.685	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,956 associations by consensus.

SWT1 vs SLC39A6 — BRCA

Explore this scatter interactively →