SWT1

Across TCGA cell cohorts, SWT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,467 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SWT1-associated GO terms across cancer lineages are Regulation of autophagosome assembly, Regulation of vacuole organization, and Negative regulation of hematopoietic stem cell differentiation. Each is linked with SWT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SWT1-to-partner and partner-to-SWT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of autophagosome assembly grouped by SWT1-low versus SWT1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SWT1→partner) and Y-score (partner→SWT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of autophagosome assembly →	+0.092	+0.803	.002	<.001	3	14
STOMACH	Regulation of vacuole organization →	+0.096	+0.738	.001	<.001	3	13
PANCREAS	Negative regulation of hematopoietic stem cell differentiation →	+0.111	+0.392	<.001	.001	3	12
STOMACH	Golgi vesicle transport →	+0.075	+0.747	<.001	<.001	3	12
SKIN	Establishment of vesicle localization →	+0.039	+0.368	.001	.006	3	12
PANCREAS	Copper ion export →	-0.212	-0.507	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,467 associations by consensus.

Regulation of autophagosome assembly by SWT1 expression — STOMACH

Explore this box plot interactively →