SWSAP1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SWSAP1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SWSAP1 data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher SWSAP1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SWSAP1 expression acts as an unfavorable survival marker.

THCA, BLCA, and SKCM are the cancer types where SWSAP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCADFSMedianAll0.0700.896<.00118view →
BLCAOSMedianIV0.0570.600<.00112view →
SKCMOSMedianAll0.1790.781<.0019view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SWSAP1–THCA (DFS)

Kaplan–Meier survival curve for SWSAP1 mutant vs wild-type samples in THCA.

Open the THCA breakdown →

Exploration