SWI5

Across TCGA pan-cancer cohorts, SWI5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SWI5 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SWI5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SWI5 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where SWI5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.424	1.000	.036	7	view →
LSCC	OS	Tertile	II,III,IV	0.898	0.586	.028	6	view →
LUAD	DFS	Median	All	1.000	0.658	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SWI5–CCRCC (OS)

Open the CCRCC breakdown →