SWI5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SWI5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,739 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SWI5-associated genes across cancer lineages are TAF12, ATRAID, and SLC39A1. Each is linked with SWI5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SWI5-to-partner and partner-to-SWI5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SWI5 versus TAF12 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SWI5→partner) and Y-score (partner→SWI5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATAF12 →+0.539+0.332<.001.00133
UCECATRAID →+0.938+0.655.002.00733
GBMSLC39A1 →+0.417+0.908<.001<.00132
GBMLINC01116 →-1.461-0.726.006.00732
GBMRN7SL402P →+0.426+0.827.001<.00132
CCRCCSTAB2 →-1.347-0.665.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,739 associations by consensus.

SWI5 vs TAF12 — BRCA

Per-sample scatter of SWI5 vs TAF12 in BRCA (Pearson r = 0.45).

Explore this scatter interactively →

Exploration