SWI5

Across TCGA cell cohorts, SWI5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,398 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SWI5-associated GO terms across cancer lineages are Meiotic DNA recombinase assembly, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Body fluid secretion. Each is linked with SWI5 in more than 15 cancer types. Because this analysis shows association rather than direction, both SWI5-to-partner and partner-to-SWI5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic DNA recombinase assembly grouped by SWI5-low versus SWI5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SWI5→partner) and Y-score (partner→SWI5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Meiotic DNA recombinase assembly →	+0.135	+1.058	<.001	<.001	3	16
BONE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.085	+0.888	<.001	.001	3	12
SOFT_TISSUE	Body fluid secretion →	-0.139	-0.905	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Proteasome regulatory particle assembly →	+0.139	+0.999	<.001	.001	3	10
LARGE_INTESTINE	Protein localization to early endosome →	+0.169	+0.749	<.001	.002	3	9
OESOPHAGUS	Mitochondrial depolarization →	+0.149	+0.891	.003	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,398 associations by consensus.

Meiotic DNA recombinase assembly by SWI5 expression — OVARY

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