SWAP70

Across TCGA pan-cancer cohorts, SWAP70 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SWAP70 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SWAP70 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SWAP70 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

COAD, HNSC, and LUAD are the cancer types where SWAP70 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	0.826	1.000	.023	6	view →
HNSC	OS	Tertile	III,IV	1.000	0.538	.040	4	view →
LUAD	DFS	Median	III,IV	0.308	0.693	.005	3	view →
CCRCC	OS	Quartile	All	1.000	0.626	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SWAP70–COAD (DFS)

Open the COAD breakdown →