SWAP70

Across TCGA cell cohorts, SWAP70 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SWAP70-associated genes across cancer lineages are CRX, NEUROG1, and S100A7A. Each is linked with SWAP70 in more than 1 cancer types. Because this analysis shows association rather than direction, both SWAP70-to-partner and partner-to-SWAP70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRX grouped by SWAP70-low versus SWAP70-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SWAP70→partner) and Y-score (partner→SWAP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CRX →	+0.019	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	NEUROG1 →	+0.004	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	S100A7A →	+0.026	+4.643	<.001	.005	3	1
CNS	LGALS13 →	+0.126	+4.981	<.001	.008	3	1
CNS	IL3 →	+0.031	+4.981	<.001	.008	3	1
CNS	SCGB1C1 →	+0.253	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

CRX by SWAP70 expression — BLOOD_Lymphoma

Explore this box plot interactively →