SVOPL

Across TCGA patient cohorts, SVOPL RNA expression is significantly associated with the protein abundance of many other proteins, with 9,125 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SVOPL-associated proteins across cancer lineages are ZNF219_S698, ZMYM3, and ZNF219_S114. Each is linked with SVOPL in more than 3 cancer types. Because this analysis shows association rather than direction, both SVOPL-to-partner and partner-to-SVOPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SVOPL versus ZNF219_S698 in HNSC, with a Pearson correlation of 0.18.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SVOPL→partner) and Y-score (partner→SVOPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF219_S698 →	+0.807	+0.449	.001	<.001	3	4
LSCC	ZMYM3 →	+0.314	+0.388	.002	.005	3	3
HNSC	ZNF219_S114 →	+0.954	+0.293	<.001	.004	3	3
OV	SCCPDH →	+0.378	+0.604	.008	.007	3	3
LSCC	HSPA14 →	+0.298	+0.730	.001	<.001	3	3
UCEC	IFT88 →	+0.460	+0.630	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,125 associations by consensus.

SVOPL vs ZNF219_S698 — HNSC

Explore this scatter interactively →