SVOPL

Across TCGA cell cohorts, SVOPL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,680 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SVOPL-associated GO terms across cancer lineages are Response to indole-3-methanol, Negative regulation of mRNA metabolic process, and Desmosome assembly. Each is linked with SVOPL in more than 8 cancer types. Because this analysis shows association rather than direction, both SVOPL-to-partner and partner-to-SVOPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by SVOPL-low versus SVOPL-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SVOPL→partner) and Y-score (partner→SVOPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to indole-3-methanol →	+0.221	+0.826	<.001	<.001	3	9
OVARY	Negative regulation of mRNA metabolic process →	+0.067	+0.703	<.001	<.001	3	8
BREAST	Desmosome assembly →	+0.245	+0.935	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of inner ear receptor cell differentiation →	+1.043	+1.542	<.001	<.001	3	7
BLOOD_Leukemia	Regulation of mechanoreceptor differentiation →	+1.043	+1.542	<.001	<.001	3	7
URINARY_TRACT	Cellular response to lithium ion →	+0.207	+0.841	.004	.005	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,680 associations by consensus.

Response to indole-3-methanol by SVOPL expression — URINARY_TRACT

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