Across TCGA patient cohorts, SVIL RNA expression is significantly associated with the protein abundance of many other proteins, with 17,171 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SVIL-associated proteins across cancer lineages are SVIL_S245, SVIL_S1322, and SVIL_S50. Each is linked with SVIL in more than 9 cancer types. Because this analysis shows association rather than direction, both SVIL-to-partner and partner-to-SVIL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SVIL→partner) and Y-score (partner→SVIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SVIL_S245 →	+1.106	+1.127	<.001	<.001	3	10
GBM	SVIL_S1322 →	+0.666	+0.853	<.001	<.001	3	8
BRCA	SVIL_S50 →	+0.674	+0.650	<.001	.004	3	7
UCEC	PARVA →	+0.436	+0.509	<.001	.002	3	7
BRCA	RSU1 →	+0.457	+1.020	<.001	<.001	3	7
BRCA	SEC23B →	-0.340	-0.794	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,171 associations by consensus.

Exploration

SVIL survival (RNA) · tumor vs normal (RNA) · all SVIL data types