SVBP

Across TCGA cell cohorts, SVBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,436 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SVBP-associated GO terms across cancer lineages are Mitotic cell cycle phase transition, DNA geometric change, and Chromosome condensation. Each is linked with SVBP in more than 10 cancer types. Because this analysis shows association rather than direction, both SVBP-to-partner and partner-to-SVBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cell cycle phase transition grouped by SVBP-low versus SVBP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SVBP→partner) and Y-score (partner→SVBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitotic cell cycle phase transition →	+0.095	+1.246	<.001	<.001	3	11
SKIN	DNA geometric change →	+0.075	+0.593	<.001	<.001	3	11
BONE	Chromosome condensation →	+0.153	+1.128	.004	.001	3	10
LUNG_NSCLC_LUAD	Microtubule cytoskeleton organization involved in mitosis →	+0.071	+0.757	<.001	<.001	3	10
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.077	+1.102	.001	<.001	3	10
BREAST	Regulation of DNA-templated transcription initiation →	+0.062	+1.048	.003	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,436 associations by consensus.

Mitotic cell cycle phase transition by SVBP expression — BONE

Explore this box plot interactively →