Across TCGA cell cohorts, SV2B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,717 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SV2B-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, DNA replication-dependent chromatin disassembly, and Negative regulation of RNA catabolic process. Each is linked with SV2B in more than 5 cancer types. Because this analysis shows association rather than direction, both SV2B-to-partner and partner-to-SV2B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SV2B→partner) and Y-score (partner→SV2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.074	+1.948	.004	.003	3	6
SOFT_TISSUE	DNA replication-dependent chromatin disassembly →	+0.073	+0.032	.001	.005	3	5
LARGE_INTESTINE	Negative regulation of RNA catabolic process →	+0.041	+0.014	.009	.009	2	6
LARGE_INTESTINE	RNA destabilization →	+0.036	+0.022	<.001	.006	3	5
LARGE_INTESTINE	mRNA destabilization →	+0.038	+0.023	<.001	.004	3	5
BONE	Positive regulation of translation →	+0.044	+1.734	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,717 associations by consensus.

Exploration

SV2B survival (RNA) · tumor vs normal (RNA) · all SV2B data types