SV2A

Across TCGA patient cohorts, SV2A protein abundance is significantly associated with the protein abundance of many other proteins, with 16,677 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SV2A-associated proteins across cancer lineages are BPTF_S763, CTSC, and UQCRC1_S107. Each is linked with SV2A in more than 2 cancer types. Because this analysis shows association rather than direction, both SV2A-to-partner and partner-to-SV2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SV2A versus BPTF_S763 in LUAD, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SV2A→partner) and Y-score (partner→SV2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BPTF_S763 →	+0.922	+1.889	.001	.003	3	3
GBM	CTSC →	-0.782	-0.901	<.001	<.001	3	3
LUAD	UQCRC1_S107 →	+0.995	+1.694	.004	.002	3	2
PDAC	SZT2 →	+0.401	+1.021	<.001	.001	3	2
PDAC	TCOF1_S1350 →	-0.923	-1.020	.003	<.001	3	2
GBM	TMEM177 →	+0.591	+1.079	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,677 associations by consensus.

SV2A vs BPTF_S763 — LUAD

Explore this scatter interactively →