SUZ12

Across TCGA patient cohorts, SUZ12 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,518 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SUZ12-associated proteins across cancer lineages are CDC73, NCAPH, and MCM2. Each is linked with SUZ12 in more than 7 cancer types. Because this analysis shows association rather than direction, both SUZ12-to-partner and partner-to-SUZ12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SUZ12 versus CDC73 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SUZ12→partner) and Y-score (partner→SUZ12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CDC73 →	+0.273	+0.427	<.001	.002	3	8
GBM	NCAPH →	+0.702	+0.555	<.001	<.001	3	7
GBM	MCM2 →	+0.578	+0.305	<.001	.001	3	7
GBM	MCM3 →	+0.828	+0.580	<.001	<.001	3	7
GBM	MCM4 →	+0.584	+0.295	<.001	.002	3	7
GBM	MCM5 →	+0.700	+0.420	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,518 associations by consensus.

SUZ12 vs CDC73 — COAD

Explore this scatter interactively →