SUV39H2

Across TCGA cell cohorts, SUV39H2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,088 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SUV39H2-associated GO terms across cancer lineages are Negative regulation of chromosome segregation, DNA replication initiation, and Regulation of mitotic sister chromatid separation. Each is linked with SUV39H2 in more than 19 cancer types. Because this analysis shows association rather than direction, both SUV39H2-to-partner and partner-to-SUV39H2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome segregation grouped by SUV39H2-low versus SUV39H2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUV39H2→partner) and Y-score (partner→SUV39H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of chromosome segregation →	+0.140	+0.812	.002	.003	3	20
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.184	+1.552	<.001	<.001	3	19
BREAST	Regulation of mitotic sister chromatid separation →	+0.162	+0.999	<.001	<.001	3	19
BLOOD_Myeloma	Regulation of metaphase/anaphase transition of cell cycle →	+0.124	+1.127	.001	.001	3	19
URINARY_TRACT	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.144	+0.851	.004	.004	3	19
URINARY_TRACT	Negative regulation of chromosome separation →	+0.144	+0.851	.004	.004	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,088 associations by consensus.

Negative regulation of chromosome segregation by SUV39H2 expression — URINARY_TRACT

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