SUV39H1

Across TCGA cell cohorts, SUV39H1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,418 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SUV39H1-associated GO terms across cancer lineages are Nucleolar chromatin organization, Pericentric heterochromatin formation, and Mitotic spindle elongation. Each is linked with SUV39H1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SUV39H1-to-partner and partner-to-SUV39H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar chromatin organization grouped by SUV39H1-low versus SUV39H1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUV39H1→partner) and Y-score (partner→SUV39H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Nucleolar chromatin organization →	+0.168	+1.212	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Pericentric heterochromatin formation →	+0.175	+1.394	<.001	<.001	3	20
BONE	Mitotic spindle elongation →	+0.275	+1.021	.001	.001	3	19
BONE	Mitotic spindle midzone assembly →	+0.275	+1.021	.001	.001	3	19
LUNG_NSCLC_LUSC	Nucleolus organization →	+0.130	+1.062	<.001	<.001	3	19
BONE	Regulation of cell cycle checkpoint →	+0.127	+1.181	.006	.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,418 associations by consensus.

Nucleolar chromatin organization by SUV39H1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →