SUV39H1

Across TCGA cell cohorts, SUV39H1 mutation is significantly associated with the mutation status of many other genes, with 488 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SUV39H1-associated genes across cancer lineages are GPSM1, FBXL16, and INTS10. Each is linked with SUV39H1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUV39H1-to-partner and partner-to-SUV39H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPSM1 grouped by SUV39H1-low versus SUV39H1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUV39H1→partner) and Y-score (partner→SUV39H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPSM1 →	+3.823	+4.430	.001	.001	1	3
LARGE_INTESTINE	FBXL16 →	+4.523	+5.087	.006	.006	1	3
BLOOD_Leukemia	INTS10 →	+4.560	+4.309	.007	.007	1	2
BLOOD_Leukemia	GALNT18 →	+3.823	+4.430	.001	.001	1	2
BLOOD_Leukemia	ALDH5A1 →	+5.560	+4.736	.003	.003	1	2
BLOOD_Leukemia	PIK3R3 →	+4.560	+4.309	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 488 associations by consensus.

GPSM1 by SUV39H1 expression — BLOOD_Leukemia

Explore this box plot interactively →