SUSD6

Across TCGA patient cohorts, SUSD6 mutation is significantly associated with the RNA expression of many other genes, with 975 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUSD6-associated genes across cancer lineages are FAM242E, CRYBB2P1, and SRRD. Each is linked with SUSD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUSD6-to-partner and partner-to-SUSD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM242E grouped by SUSD6-low versus SUSD6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUSD6→partner) and Y-score (partner→SUSD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FAM242E →	+0.034	+7.741	<.001	.009	3	2
UCEC	CRYBB2P1 →	+0.509	+2.243	.003	.006	3	1
UCEC	SRRD →	+0.432	+3.625	.008	.001	3	1
UCEC	RTCB →	+0.518	+3.224	.005	.009	3	1
UCEC	JOSD1 →	+0.450	+3.609	.008	.001	3	1
UCEC	FBXO7 →	+0.430	+2.928	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 975 associations by consensus.

FAM242E by SUSD6 expression — COAD

Explore this box plot interactively →