SUSD5

Across TCGA patient cohorts, SUSD5 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUSD5-associated genes across cancer lineages are TFRC, Caspase-7-cleavedD198, and Shc_pY317. Each is linked with SUSD5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUSD5-to-partner and partner-to-SUSD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by SUSD5-low versus SUSD5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUSD5→partner) and Y-score (partner→SUSD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.528	+2.459	.008	.018	3	3
UCEC	Caspase-7-cleavedD198 →	+0.680	+1.720	.002	.025	3	3
COAD	Shc_pY317 →	-0.229	-2.987	.005	.035	3	2
UCEC	ERK2 →	+0.232	+2.169	.001	.003	3	2
UCEC	FoxM1 →	+0.202	+1.415	.037	.046	3	2
UCEC	JNK_pT183_Y185 →	-0.209	-2.807	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

TFRC by SUSD5 expression — UCEC

Explore this box plot interactively →