SUSD2

Across TCGA pan-cancer cohorts, SUSD2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SUSD2 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SUSD2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SUSD2 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

LSCC, COAD, and PDAC are the cancer types where SUSD2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.857	1.000	.006	28	view →
COAD	DFS	Tertile	All	0.852	1.000	.027	24	view →
PDAC	OS	Quartile	II,III,IV	0.712	0.274	.002	18	view →
CCRCC	DFS	Median	All	0.883	0.625	.004	18	view →
GBM	OS	Tertile	All	0.695	0.977	.001	16	view →
LUAD	OS	Median	All	0.895	0.767	.012	7	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SUSD2–LSCC (DFS)

Open the LSCC breakdown →