SUSD2

Across TCGA patient cohorts, SUSD2 mutation is significantly associated with the RNA expression of many other genes, with 707 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SUSD2-associated genes across cancer lineages are MIR190B, HAGLROS, and PTGER4P3. Each is linked with SUSD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUSD2-to-partner and partner-to-SUSD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR190B grouped by SUSD2-low versus SUSD2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUSD2→partner) and Y-score (partner→SUSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR190B →	+0.214	+4.423	<.001	.007	3	3
SKCM	HAGLROS →	-0.838	-3.794	.003	<.001	3	3
LUAD	PTGER4P3 →	+0.429	+5.066	<.001	<.001	3	3
LUSC	RNA5SP415 →	+1.086	+5.733	<.001	.001	3	3
GBM	RNU1-117P →	+0.422	+5.857	<.001	.002	3	2
LIHC	MIR6070 →	+0.215	+4.293	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 707 associations by consensus.

MIR190B by SUSD2 expression — LIHC

Explore this box plot interactively →