SUSD2

Across TCGA cell cohorts, SUSD2 mutation is significantly associated with the RNA expression of many other genes, with 178 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SUSD2-associated genes across cancer lineages are C12orf65, NR0B2, and OXNAD1. Each is linked with SUSD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUSD2-to-partner and partner-to-SUSD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C12orf65 grouped by SUSD2-low versus SUSD2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUSD2→partner) and Y-score (partner→SUSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C12orf65 →	+0.426	+3.234	.006	.004	3	2
LARGE_INTESTINE	NR0B2 →	+1.063	+3.364	.006	.002	3	2
LARGE_INTESTINE	OXNAD1 →	+0.461	+3.364	.003	.002	3	2
LARGE_INTESTINE	ADORA3 →	+0.034	+3.921	.004	<.001	3	2
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	2
BREAST	PABPC1L2A →	+0.083	+5.169	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 178 associations by consensus.

C12orf65 by SUSD2 expression — LARGE_INTESTINE

Explore this box plot interactively →