SUSD1

Across TCGA patient cohorts, SUSD1 mutation is significantly associated with the RNA expression of many other genes, with 4,038 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUSD1-associated genes across cancer lineages are TRAJ1, HERC2P1, and RNA5SP73. Each is linked with SUSD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUSD1-to-partner and partner-to-SUSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ1 grouped by SUSD1-low versus SUSD1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUSD1→partner) and Y-score (partner→SUSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TRAJ1 →	+1.092	+4.274	<.001	.008	3	3
UCEC	HERC2P1 →	+0.015	+2.327	<.001	.008	3	3
PAAD	RNA5SP73 →	+0.352	+5.392	<.001	.005	3	2
HNSC	RN7SKP208 →	+0.135	+4.716	.002	.003	3	2
HNSC	MIR572 →	+0.319	+4.912	<.001	.005	3	2
LIHC	RNU6-1147P →	+0.398	+4.544	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,038 associations by consensus.

TRAJ1 by SUSD1 expression — LIHC

Explore this box plot interactively →