SURF2

Across TCGA patient cohorts, SURF2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SURF2-associated genes across cancer lineages are Macrophages M1 and Endothelial cells. Each is linked with SURF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SURF2-to-partner and partner-to-SURF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macrophages M1 grouped by SURF2-low versus SURF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SURF2→partner) and Y-score (partner→SURF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Macrophages M1 →	+0.024	+2.864	.005	.049	3	1
UCEC	Endothelial cells →	-0.047	-2.957	.032	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Macrophages M1 by SURF2 expression — UCEC

Explore this box plot interactively →