SURF2

Across TCGA cell cohorts, SURF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,800 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SURF2-associated GO terms across cancer lineages are Spliceosomal snRNP assembly, Spliceosomal tri-snRNP complex assembly, and Ribosome biogenesis. Each is linked with SURF2 in more than 15 cancer types. Because this analysis shows association rather than direction, both SURF2-to-partner and partner-to-SURF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal snRNP assembly grouped by SURF2-low versus SURF2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SURF2→partner) and Y-score (partner→SURF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Spliceosomal snRNP assembly →	+0.088	+1.151	<.001	<.001	3	16
STOMACH	Spliceosomal tri-snRNP complex assembly →	+0.133	+1.064	.004	.003	2	16
BONE	Ribosome biogenesis →	+0.152	+1.293	<.001	<.001	3	15
BONE	Maturation of 5.8S rRNA →	+0.108	+0.683	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Transcription by RNA polymerase III →	+0.084	+0.821	.009	.001	3	15
BLOOD_Myeloma	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.119	+0.887	<.001	.004	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,800 associations by consensus.

Spliceosomal snRNP assembly by SURF2 expression — BLOOD_Lymphoma

Explore this box plot interactively →