SURF1

Across TCGA pan-cancer cohorts, SURF1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SURF1 data layer compared with 20 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher SURF1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SURF1 expression acts as an unfavorable survival marker.

MESO are the cancer types where SURF1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

SURF1–MESO (DFS)

Open the MESO breakdown →