SURF1

Across TCGA cell cohorts, SURF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,772 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SURF1-associated GO terms across cancer lineages are COPII vesicle coating, Vesicle targeting, rough ER to cis-Golgi, and Vesicle coating. Each is linked with SURF1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SURF1-to-partner and partner-to-SURF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII vesicle coating grouped by SURF1-low versus SURF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SURF1→partner) and Y-score (partner→SURF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	COPII vesicle coating →	+0.122	+1.003	<.001	<.001	3	11
BONE	Vesicle targeting, rough ER to cis-Golgi →	+0.115	+0.916	<.001	<.001	3	10
CNS	Vesicle coating →	+0.076	+0.725	<.001	<.001	3	10
BONE	COPII-coated vesicle budding →	+0.073	+0.685	.004	.005	3	9
OVARY	Iron-sulfur cluster assembly →	+0.091	+1.021	<.001	<.001	3	9
OVARY	Metallo-sulfur cluster assembly →	+0.091	+1.021	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,772 associations by consensus.

COPII vesicle coating by SURF1 expression — BONE

Explore this box plot interactively →