SUPV3L1

Across TCGA pan-cancer cohorts, SUPV3L1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SUPV3L1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SUPV3L1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SUPV3L1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where SUPV3L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.600	0.879	.002	26	view →
LSCC	DFS	Quartile	II,III,IV	0.948	0.620	.016	6	view →
LUAD	OS	Quartile	II,III,IV	0.363	1.000	.020	4	view →
GBM	DFS	Median	All	0.792	0.646	.025	4	view →
UCEC	DFS	Median	All	0.934	1.000	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SUPV3L1–CCRCC (DFS)

Open the CCRCC breakdown →