SUPV3L1

Across TCGA cell cohorts, SUPV3L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,761 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SUPV3L1-associated GO terms across cancer lineages are Regulation of mitochondrial RNA catabolic process, Positive regulation of mitochondrial RNA catabolic process, and Mitochondrial DNA repair. Each is linked with SUPV3L1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SUPV3L1-to-partner and partner-to-SUPV3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial RNA catabolic process grouped by SUPV3L1-low versus SUPV3L1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPV3L1→partner) and Y-score (partner→SUPV3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of mitochondrial RNA catabolic process →	+0.160	+0.807	.002	.004	2	20
LUNG_SCLC	Positive regulation of mitochondrial RNA catabolic process →	+0.165	+0.810	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Mitochondrial DNA repair →	+0.164	+0.755	.002	<.001	3	14
BONE	Mitochondrial RNA catabolic process →	+0.150	+0.724	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Pseudouridine synthesis →	+0.120	+1.074	<.001	<.001	3	13
SOFT_TISSUE	Mitochondrial RNA 3'-end processing →	+0.131	+0.730	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Regulation of mitochondrial RNA catabolic process by SUPV3L1 expression — LIVER

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