SUPV3L1

Across TCGA cell cohorts, SUPV3L1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SUPV3L1-associated genes across cancer lineages are OR10R2, SCYGR2, and ZNF831. Each is linked with SUPV3L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPV3L1-to-partner and partner-to-SUPV3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by SUPV3L1-low versus SUPV3L1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPV3L1→partner) and Y-score (partner→SUPV3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10R2 →	+1.482	+3.551	<.001	.009	3	2
URINARY_TRACT	SCYGR2 →	+0.243	+5.087	<.001	.004	3	1
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.410	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.227	+4.095	<.001	.009	3	1
BLOOD_Leukemia	ADRA1A →	+0.180	+3.705	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

OR10R2 by SUPV3L1 expression — BLOOD_Leukemia

Explore this box plot interactively →