Across TCGA pan-cancer cohorts, SUPT5H Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated SUPT5H data layer compared with 29 for mass-spec protein and 4 for mass-spec protein.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SUPT5H Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated SUPT5H expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.
UCEC, STAD, and READ are the cancer types where SUPT5H Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.