Across TCGA pan-cancer cohorts, SUPT5H mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SUPT5H data layer compared with 29 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SUPT5H mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SUPT5H expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, HNSC, and LUAD are the cancer types where SUPT5H mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.954	0.690	.009	8	view →
HNSC	OS	Median	II,III,IV	1.000	0.953	.019	4	view →
LUAD	DFS	Median	All	1.000	0.893	.019	3	view →
CCRCC	DFS	Tertile	All	0.711	1.000	.028	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SUPT5H tumor-vs-normal RNA expression · all SUPT5H data types