Across TCGA patient cohorts, SUPT5H mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT5H-associated genes across cancer lineages are Caspase-8, Cyclin-B1, and Caveolin-1. Each is linked with SUPT5H in more than 2 cancer types. Because this analysis shows association rather than direction, both SUPT5H-to-partner and partner-to-SUPT5H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT5H→partner) and Y-score (partner→SUPT5H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-8 →	-0.215	-2.636	.005	<.001	3	3
UCEC	Cyclin-B1 →	+0.383	+1.807	.026	.024	3	3
SKCM	Caveolin-1 →	-0.821	-2.906	.001	.001	3	3
UCEC	Ku80 →	+0.179	+1.077	.013	.032	3	2
UCEC	MEK1 →	+0.302	+1.999	.007	.002	3	2
UCEC	MSH2 →	-0.246	-2.061	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

SUPT5H survival (RNA) · tumor vs normal (RNA) · all SUPT5H data types