Across TCGA cell cohorts, SUPT5H mutation is significantly associated with the RNA expression of many other genes, with 1,515 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SUPT5H-associated genes across cancer lineages are SETD1B, C9orf57, and OR2M4. Each is linked with SUPT5H in more than 2 cancer types. Because this analysis shows association rather than direction, both SUPT5H-to-partner and partner-to-SUPT5H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT5H→partner) and Y-score (partner→SUPT5H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SETD1B →	+0.576	+2.158	.002	.004	3	3
LUNG_SCLC	C9orf57 →	+0.028	+3.578	.005	<.001	3	2
OVARY	OR2M4 →	+0.060	+3.700	<.001	.005	3	2
LUNG_SCLC	POTED →	+0.019	+3.169	<.001	.005	3	2
LARGE_INTESTINE	PPM1A →	+0.531	+3.584	<.001	<.001	3	2
LARGE_INTESTINE	ZNF451 →	+0.556	+2.526	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,515 associations by consensus.

Exploration

SUPT5H survival (RNA) · tumor vs normal (RNA) · all SUPT5H data types