Across TCGA pan-cancer cohorts, SUPT4H1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SUPT4H1 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SUPT4H1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SUPT4H1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

UCEC, CCRCC, and PDAC are the cancer types where SUPT4H1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.894	1.000	.011	30	view →
CCRCC	DFS	Quartile	All	0.792	1.000	.014	5	view →
PDAC	DFS	Quartile	III,IV	0.941	0.377	.008	5	view →
LUAD	DFS	Median	All	0.732	0.528	.013	4	view →
HNSC	DFS	Median	III,IV	1.000	0.939	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: SUPT4H1 tumor-vs-normal RNA expression · all SUPT4H1 data types