Across TCGA patient cohorts, SUPT4H1 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT4H1-associated genes across cancer lineages are Notch1, Claudin-7, and MEK1. Each is linked with SUPT4H1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPT4H1-to-partner and partner-to-SUPT4H1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT4H1→partner) and Y-score (partner→SUPT4H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.145	+3.459	.040	.005	3	1
UCEC	Claudin-7 →	-0.587	-2.321	.020	.035	3	1
UCEC	MEK1 →	+0.487	+3.169	.007	.019	2	1
UCEC	JNK2 →	+0.232	+2.321	.020	.035	1	1
UCEC	Chk1 →	-0.183	-2.321	.027	.035	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SUPT4H1 survival (RNA) · tumor vs normal (RNA) · all SUPT4H1 data types