Across TCGA pan-cancer cohorts, SUPT3H mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SUPT3H data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SUPT3H mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SUPT3H expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

PDAC, GBM, and LUAD are the cancer types where SUPT3H mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.279	0.753	.004	14	view →
GBM	OS	Median	All	0.684	0.480	.044	4	view →
LUAD	DFS	Median	III,IV	1.000	0.498	.017	3	view →
CCRCC	DFS	Median	II,III,IV	0.514	0.849	.012	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SUPT3H tumor-vs-normal RNA expression · all SUPT3H data types