Across TCGA patient cohorts, SUPT3H mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT3H-associated genes across cancer lineages are Smad3, ASNS, and Cyclin-E2. Each is linked with SUPT3H in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPT3H-to-partner and partner-to-SUPT3H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT3H→partner) and Y-score (partner→SUPT3H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Smad3 →	+0.120	+2.115	.047	.017	3	2
UCEC	ASNS →	+0.424	+2.459	.003	.018	3	2
UCEC	Cyclin-E2 →	+0.153	+1.906	.023	.016	3	2
UCEC	14-3-3_beta →	-0.125	-3.432	.001	.005	3	1
UCEC	eEF2 →	+0.426	+1.906	.003	.016	3	1
UCEC	EGFR →	-0.201	-2.295	.001	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

SUPT3H survival (RNA) · tumor vs normal (RNA) · all SUPT3H data types