SUPT3H

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SUPT3H mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SUPT3H-associated genes across cancer lineages are OBP2B, NPSR1, and KRTAP12-3. Each is linked with SUPT3H in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPT3H-to-partner and partner-to-SUPT3H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT3H→partner) and Y-score (partner→SUPT3H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOBP2B →+0.057+5.269<.001<.00131
BLOOD_LeukemiaNPSR1 →+0.033+4.152<.001.00931
BLOOD_LeukemiaKRTAP12-3 →+0.092+4.539<.001.00731
BLOOD_LeukemiaSTH →+0.058+4.874.003.00231
BLOOD_LeukemiaTBX5 →+0.227+4.276<.001.00731
CNSCFHR2 →+0.076+6.357<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

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