Across TCGA patient cohorts, SUPT20HL1 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT20HL1-associated genes across cancer lineages are STAT3_pY705, 4E-BP1, and Cyclin-B1. Each is linked with SUPT20HL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPT20HL1-to-partner and partner-to-SUPT20HL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT20HL1→partner) and Y-score (partner→SUPT20HL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.360	-2.105	<.001	.017	3	2
UCEC	4E-BP1 →	+0.439	+3.000	<.001	.001	3	2
UCEC	Cyclin-B1 →	+0.618	+3.321	.007	.009	3	2
UCEC	14-3-3_beta →	-0.098	-2.295	.018	.033	3	1
UCEC	eEF2 →	+0.415	+3.169	.004	.018	3	1
UCEC	A-Raf_pS299 →	-0.144	-2.459	.003	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

SUPT20HL1 survival (RNA) · tumor vs normal (RNA) · all SUPT20HL1 data types