SUOX

Across TCGA pan-cancer cohorts, SUOX mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SUOX data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SUOX mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SUOX expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and PDAC are the cancer types where SUOX mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	1.000	0.836	.003	49	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.306	.001	27	view →
PDAC	OS	Tertile	III,IV	0.968	0.305	.003	19	view →
HNSC	DFS	Quartile	II,III,IV	0.875	0.981	.021	7	view →
UCEC	OS	Tertile	II,III,IV	0.650	1.000	.038	4	view →
LSCC	OS	Tertile	II,III,IV	0.618	0.948	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SUOX–CCRCC (OS)

Open the CCRCC breakdown →