SUN5

Across TCGA patient cohorts, SUN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,449 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SUN5-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Proton motive force-driven ATP synthesis, and Virion assembly. Each is linked with SUN5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SUN5-to-partner and partner-to-SUN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by SUN5-low versus SUN5-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUN5→partner) and Y-score (partner→SUN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of double-strand break repair via homologous recombination →	+0.073	+0.164	<.001	.003	3	9
STAD	Proton motive force-driven ATP synthesis →	+0.097	+0.165	<.001	<.001	3	9
STAD	Virion assembly →	+0.061	+0.182	<.001	<.001	3	9
STAD	Mitochondrial translation →	+0.091	+0.185	<.001	<.001	3	9
STAD	Regulation of polysaccharide metabolic process →	+0.058	+0.164	<.001	<.001	3	9
STAD	Protein localization to mitochondrion →	+0.077	+0.196	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,449 associations by consensus.

Regulation of double-strand break repair via homologous recombination by SUN5 expression — ESCA

Explore this box plot interactively →